iMiGiNE: Automated Radiopharmaceutical Production System

iMiGiNE is a robotized system capable of producing various radiopharmaceuticals used in PET imaging
imigine radiopharmaceutical production system by pmb
imigine radiopharmaceutical production system by pmb

With iMiGiNE, personalized molecular imaging becomes a reality. 

It is a cutting-edge automated system for the production of radiopharmaceuticals used in PET imaging. Compact and fully robotized, it offers an alternative to the heavy traditional radiopharmaceutical production processes and grants imaging centers access to a variety of molecules, at a low cost.

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  • It combines a cyclotron ISOTRACE with a radiochemistry room iMiLAB, complete with an automated QC system
  • Superconducting magnet technology, external self-shielded beam
  • Automated target changer
  • Automated syringe dispenser, including high-precision activity measurement and traceability

For a few years now, with various collaborators, PMB has been designing and developing a cutting-edge automated system for the production of radiopharmaceuticals used in PET imaging. More than just another radiopharmaceutical dispenser, we have envisioned a system designed to improve and optimize patient care, while providing new grounds to further research in the medical imaging field. Due to its proximity with patients and research centers, iMiGiNe will help better detect and characterize disease and allow for a same day diagnosis with multiple radiotracers. 


imigine automated radiopharmaceutical production system for pet imaging

ISOTRACE cyclotron

  • Accelerates Particles to 12 MeV: ideal energy for the production of 18F, 11C, 68Ga and more
  • He-free Superconducting Magnet
  • Four External Targets
  • Self-shielded targetry
  • Lightweight and Compact
  • Reliable 

Specifically designed for imaging centers, the cyclotron ISOTRACE grants them access to an on-site radiopharmaceutical production system. Reliable, stable and compact, ISOTRACE is entirely designed and manufactured at PMB. With a self-shielded, 4-port targetry and equipped with a helium-free superconducting magnet, ISOTRACE is the result of many technological improvements made to cyclotron OSCAR (Oxford Instruments). 


cyclotron isotrace by pmb

iMiLAB radiochemistry

  • Microfluidic-Based Synthesis
  • One Dose One Patient
  • Automated Syringe Filling
  • Self-shielded
  • Reduced Radiation Exposure
  • Multiple Radiopharmaceuticals Produced with 18F, 11C, 68Ga and more

The radiochemistry room iMiLAB is compact and self-shielded. Entirely robotized and GMP compliant, the iMiLAB radiochemistry room utilizes micro-fluidic techniques capable of producing diversified radiopharmaceuticals in an automated synthesis box and in sterile cartridges with onboard precursors and solvents. It is capable of synthetizing multiple molecules on a same-day basis, with a decreased need in staff. 


imilab radiochemistry room for pet imaging